動物劑量與人體可用劑量交換

人體等酵劑量（mg/kg）= 動物劑量（mg/kg）×動物Km÷人體Km
The FASEB Journal • Life Sciences Forum
Dose translation from animal to human studies revisited
Shannon Reagan-Shaw,* Minakshi Nihal,*,† and Nihal Ahmad*,†,‡,1
*Department of Dermatology, †Paul P. Carbone Comprehensive Cancer Center; ‡Molecular and
Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin, USA